Enlarge / A vial containing Moderna COVID-19 booster vaccine at a vaccination center. (credit: Getty | SOPA Images)
COVID-19 booster doses are largely holding up against the ultratransmissible omicron variant, despite the fact that protection inevitably wanes over time, according to a recent study published by the Centers for Disease Control and Prevention.
Still, with the boosters' inevitable waning and omicron's ability to dodge some immune responses, fourth doses may be needed in the future to sustain or improve protection against COVID-19, the study authors note.
The study, published in the CDC's Morbidity and Mortality Weekly Report, estimated booster effectiveness against severe disease and hospitalizations. It charted a slight decline in booster effectiveness from less than two months after a booster dose to over four or five months after the third jab. The latter time frame is the latest for which there is available booster data, based on when the shots became widely offered. The study collected data from patients in 10 states, including from over 240,000 visits to emergency rooms or urgent care centers and more than 93,000 hospitalizations.
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