Moderna and Merck say their mRNA cancer vaccine cut death, recurrence by 42%

Moderna and Merck say their mRNA cancer vaccine cut death, recurrence by 42%

fivenewscrypto    octobre 24, 2026   

Personalized mRNA vaccines against melanoma—the deadliest form of skin cancer—reduced the risk of death or recurrence by 42 percent compared to standard treatment in a late-stage trial, pharmaceutical partners Merck and Moderna announced Thursday.

The results are a significant advance in melanoma treatment; Merck and Moderna are already engaging with regulatory authorities to get the vaccine approved. More broadly, the vaccine's success bolsters hope that mRNA vaccines and individualized cancer-targeting medicines offer a new paradigm for cancer therapies.

"From the beginning, we believed mRNA technology could make it possible to develop cancer treatments uniquely matched to each patient’s tumor," Moderna CEO Stéphane Bancel said in a statement. The trial results "mark a defining moment for that vision and show what’s possible when we rethink how medicines are made." They also "reinforce our conviction that mRNA has the potential to fundamentally change how we treat cancer," he said.

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Latest estimate for Starship launches required to support a Moon landing? 22.

Latest estimate for Starship launches required to support a Moon landing? 22.

fivenewscrypto    octobre 24, 2026   

NASA does not have, nor want, nuclear weapons. But when it comes to a particular metric that is part of the Artemis Program to land people on the Moon, NASA guards a particular number like it is trying to prevent outsiders from cracking nuclear codes.

I am speaking of the number of Starship launches required to fuel a Starship-based lunar lander in low-Earth orbit such that it can fly out to the Moon, land there, and return to lunar orbit.

This number has been a moving target over the years. The general response from NASA has typically been, 'We don't know for sure, so we're not going to say.' In 2023, for example, the then-director of NASA's Human Landing System, Lisa Watson-Morgan, told Ars, "We have a general idea, but I’m reluctant to say exactly what that is."

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Comcast loses more customers, claims other ISPs' cheap prices are "irrational"

Comcast loses more customers, claims other ISPs' cheap prices are "irrational"

fivenewscrypto    octobre 23, 2026   

Comcast reportedly plans significant job cuts in its cable division as the firm continues to lose residential broadband and TV customers. Comcast lost 144,000 residential broadband customers in Q3 2026, up from a 91,000-customer loss in the same quarter a year ago, the company said in its earnings report today.

Comcast historically capitalized on a lack of competition for high-speed wired broadband. But now it faces stronger competition from fixed wireless providers and from fiber providers in parts of its cable territory.

"Fixed wireless remains aggressive and continues to take share, while fiber construction remains elevated, with pockets of irrational pricing and promotional activity," Comcast co-CEO Mike Cavanagh said today in an earnings call.

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Disgraced eMudhra drops out of TLS business after using cert private key of 4

Disgraced eMudhra drops out of TLS business after using cert private key of 4

fivenewscrypto    octobre 23, 2026   

eMudhra, the certificate authority that issued eight intermediate TLS credentials so weak that anyone could mint certificates for any website or mail server—one had a private encryption key of just 4—said it’s getting out of the business.

V. Srinivasan, chairman of India-based eMudhra Limited, cited increasing costs and complexities of compliance requirements—paired with the business generating just 1 percent of its revenue. He also said that the emergence of organizations providing TLS certificates free of charge further reduced returns on investment when compared to other products and services the company offers.

Don't let the door hit you on the butt

“However, the level of social media amplification around this incident has brought scrutiny that is out of proportion to SSL/TLS’s place in our business,” the company continued in a Thursday post. “In view of this, after detailed deliberations our board has concluded that withdrawing from global SSL/TLS is the right decision for eMudhra and its shareholders.”

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Leaked Mass Effect: Universe trailer gives a taste of what we're all missing

Leaked Mass Effect: Universe trailer gives a taste of what we're all missing

fivenewscrypto    octobre 23, 2026   

Those mourning yesterday's shuttering of highly praised and influential developer BioWare also had to deal with the cancellation of the next Mass Effect game, which was first teased back in 2020. Today, we got our best look at what that game could have been with a short, leaked trailer for Mass Effect: Universe.

In the roughly two-minute montage—which describes itself as "in-engine footage from our small team" that "uses our pre-production assets"—an ex-military officer wearing an N7 trenchcoat (similar to the one seen in that 2020 teaser) encounters an Asari at a bar. He talks of his frustration with military life—"by the time you put out one fire, another had already started"—before discussing his new line of work "stopping [the fires] before they start" and "making the choices no one else is willing to make. Going where others are afraid to go."

Mass Effect: Universe Trailer
by
u/Random_Hyabusa_Ninja in
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Ink droplets in motion snag top prize in Nikon Small World contest

Ink droplets in motion snag top prize in Nikon Small World contest

fivenewscrypto    octobre 23, 2026   

A 25-year-old German experimental photographer has won the 2026 Nikon Small World photomicrography competition with a striking image of droplets of ink being deposited on paper by an inkjet printer. Ole Bielfeldt beat out 1,802 other entries hailing from 69 different countries.

Bielfeldt became interested in photomicrography during the COVID-19 lockdown after discovering an old microscope in his parents' attic. He figured out how to build an adaptor out of a tube and some wood to connect the microscope to his father's camera and taught himself the art through trial and error, building custom tools as needed. He documents how he captures transformative images of everyday objects with behind-the-scenes videos posted to macrofying, his photography and videography brand.

It was Bielfeldt's curiosity about the inner workings of inkjet printers that inspired his winning entry, but capturing the action of ink drops being deposited on paper was a challenge, given that the process happens so quickly. The droplets, for instance, moved faster than the camera's shutter speed. Bielfeldt's solution was to deconstruct the printer so that the paper moved under a stationary (rather than moving) printhead, and then take the image in a dark room, using a flash to serve as the shutter, thereby freezing the ink drops mid-air. There was no need for pricey equipment. Bielfeldt does not use AI in his images, preferring to rely on traditional techniques.

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Sauron recruits his future Ringwraiths in Rings of Power S3 trailer

Sauron recruits his future Ringwraiths in Rings of Power S3 trailer

fivenewscrypto    octobre 23, 2026   

Lord of the Rings: The Rings of Power returns next month for its third season. Prime Video unveiled a teaser earlier this year at San Diego Comic-Con, but we haven't heard much about the new season otherwise. We now have the official full trailer, and it's jam-packed with a rising Sauron, who is intent on conquering Middle-Earth with his army of Orcs—with the fractured opposition of elves, dwarves, and men scrambling to figure out how best to stop him. We also meet the human men who will become the Ringwraiths; the showrunners have dubbed them the Nazgnagol ("Rings-servant").

(Some spoilers for the first two seasons below.)

Prime Video made a major investment in The Rings of Power when it acquired the rights to the source material from the Tolkien estate, even committing to multiple seasons upfront. S3 is set seven years after the events of S2 and opens when the war between the elves and Sauron is at its height. Per the official synopsis:

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