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vendredi 28 novembre 2025

Many genes associated with dog behavior influence human personalities, too

Many genes associated with dog behavior influence human personalities, too

Many dog breeds are noted for their personalities and behavioral traits, from the distinctive vocalizations of huskies to the herding of border collies. People have worked to identify the genes associated with many of these behaviors, taking advantage of the fact that dogs can interbreed. But that creates its own experimental challenges, as it can be difficult to separate some behaviors from physical traits distinctive to the breed—small dog breeds may seem more aggressive simply because they feel threatened more often.

To get around that, a team of researchers recently did the largest gene/behavior association study within a single dog breed. Taking advantage of a population of over 1,000 golden retrievers, they found a number of genes associated with behaviors within that breed. A high percentage of these genes turned out to correspond to regions of the human genome that have been associated with behavioral differences as well. But, in many cases, these associations have been with very different behaviors.

Gone to the dogs

The work, done by a team based largely at Cambridge University, utilized the Golden Retriever Lifetime Study, which involved over 3,000 owners of these dogs filling out annual surveys that included information on their dogs’ behavior. Over 1,000 of those owners also had blood samples obtained from their dogs and shipped in; the researchers used these samples to scan the dogs’ genomes for variants. Those were then compared to ratings of the dogs’ behavior on a range of issues, like fear or aggression directed toward strangers or other dogs.

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There may not be a safe off-ramp for some taking GLP-1 drugs, study suggests

There may not be a safe off-ramp for some taking GLP-1 drugs, study suggests

The popularity of GLP-1 weight-loss medications continues to soar—and their uptake is helping to push down obesity rates on a national scale—but a safe, evidence-based way off the drugs isn’t yet in clear view.

An analysis published this week in JAMA Internal Medicine found that most participants in a clinical trial who were assigned to stop taking tirzepatide (Zepbound from Eli Lilly) not only regained significant amounts of the weight they had lost on the drug, but they also saw their cardiovascular and metabolic improvements slip away. Their blood pressure went back up, as did their cholesterol, hemoglobin A1c (used to assess glucose control levels), and fasting insulin.

In an accompanying editorial, two medical experts at the University of Pittsburgh, Elizabeth Oczypok and Timothy Anderson, suggest that this new class of drugs should be rebranded from “weight loss” drugs to “weight management” drugs, which people may need to take indefinitely.

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Plex’s crackdown on free remote streaming access starts this week

Plex’s crackdown on free remote streaming access starts this week

Plex is starting to enforce its new rules, which prevent users from remotely accessing a personal media server without a subscription fee.

Previously, people outside of a server owner’s network could access the owner’s media library through Plex for free. Under the new rules announced in March, a server owner needs to have a Plex Pass subscription, which starts at $7 per month, to grant users remote access to their server. Alternatively, someone can remotely access another person’s Plex server by buying their own Plex Pass or a Remote Watch Pass, which is a subscription with fewer features than a Plex Pass and that Plex started selling in April for a $2/month starting price.

Plex’s new rules took effect on April 29. According to a recent Plex forums post by a Plex employee that How-To Geek spotted today, the changes are rolling out this week, with a subscription being required for people using Plex’s Roku OS app for remote access. The Plex employee added:

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jeudi 27 novembre 2025

GPU prices are coming to earth just as RAM costs shoot into the stratosphere

GPU prices are coming to earth just as RAM costs shoot into the stratosphere

It’s not a bad time to upgrade your gaming PC. Graphics card prices in the 2020s have undulated continuously as the industry has dealt with pandemic and AI-related shortages, but it’s actually possible to get respectable mainstream- to high-end GPUs like AMD’s Radeon RX 9060 XT and 9070 series or Nvidia’s RTX 5060, 5070, and 5080 series for at or slightly under their suggested retail prices right now. This was close to impossible through the spring and summer.

But it’s not a good time to build a new PC or swap your older motherboard out for a new one that needs DDR5 RAM. And the culprit is a shortage of RAM and flash memory chips that has suddenly sent SSD and (especially) memory prices into the stratosphere, caused primarily by the ongoing AI boom and exacerbated by panic-fueled buying by end users and device manufacturers.

To illustrate just how high things have jumped in a short amount of time, let’s compare some of the RAM and storage prices listed in our system guide from three months ago to the pricing for the exact same components today. Note that several of these are based on the last available price and are currently sold out; we also haven’t looked into things like microSD or microSD Express cards, which could also be affected.

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China launches an emergency lifeboat to bring three astronauts back to Earth

China launches an emergency lifeboat to bring three astronauts back to Earth

An unpiloted Chinese spacecraft launched late Monday and linked up with the country’s Tiangong space station a few hours later, providing a lifeboat for three astronauts stuck in orbit without a safe ride home.

A Long March 2F rocket fired its engines and lifted off with the Shenzhou 22 spacecraft, carrying cargo instead of a crew, at 11:11 pm EST Monday (04:11 UTC Tuesday). The spacecraft docked with the Tiangong station nearly 250 miles (400 kilometers) above the Earth about three-and-a-half hours later.

Chinese engineers worked fast to move up the launch of the Shenzhou 22, originally set to fly next year. On November 4, astronauts discovered one of the two crew ferry ships docked to the Tiangong station had a damaged window, likely from an impact with a small fragment of space junk. The crew members used a microscope to photograph the defect from different angles, confirming a small triangular area with a crack, Zhou Jianping, chief designer of China’s human spaceflight program, told Chinese state media.

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Landlords’ go-to tool to set rent prices to be gutted under RealPage settlement

Landlords’ go-to tool to set rent prices to be gutted under RealPage settlement

RealPage has agreed to settle an antitrust lawsuit raised by the Department of Justice, alleging that landlords used its tools to coordinate efforts to artificially raise rental prices across the US.

In a press release, the DOJ promised the proposed settlement “would help restore free market competition in rental markets for millions of American renters.”

For years since the pandemic started, rental prices outpaced inflation, and the DOJ suspected that RealPage was the dominant force driving a market that never favored renters. Recent Bureau of Labor Statistics data covering a 12-month period ending this September showed rents are still rising by 3.5 percent amid an affordability crisis, leaving some US renters in fear of housing instability.

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Valve’s Steam Machine looks like a console, but don’t expect it to be priced like one

Valve’s Steam Machine looks like a console, but don’t expect it to be priced like one

After Valve announced its upcoming Steam Machine living room box earlier this month, some analysts suggested to Ars that Valve could and should aggressively subsidize that hardware with “loss leader” pricing that leads to more revenue from improved Steam software sales. In a new interview with YouTube channel Skill Up, though, Valve’s Pierre-Loup Griffais ruled out that kind of console-style pricing model, saying that the Steam Machine will be “more in line with what you might expect from the current PC market.”

Griffais said the AMD Zen 4 CPU and RDNA3 GPU in the Steam Machine were designed to outperform the bottom 70 percent of machines that opt-in to Valve’s regular hardware survey. And Steam Machine owners should expect to pay roughly what they would for desktop hardware with similar specs, he added.

“If you build a PC from parts and get to basically the same level of performance, that’s the general price window that we aim to be at,” Griffais said.

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